Omega3+6 Fettsäure

[Denise18]

Hallo,

mir wurde zur Verbesserung des trockenen Auges Ocuvite
trockenes Auge empfohlen. Es ist ein Nahrungsergänzungsmittel mit Omega 3 und 6 Fettsäuren.
Hab ich mir bestellt, obs wirkt, weiß ich leider noch nicht.
Was tut man nicht alles...

LG!

[Dr. med. Ron Lehnert]

Ja sollte wirken, in Fischöl-Konzentrat sind Wirkstoffe wie Docosahexaensäure (DHA) und Eicosapentaensäure (EPA), welche im experimentellen PRK-Tiermodell in Kombination mit Nerveneachstumsfakor (NGF) die Hornhautnervregeneration verbesserte:

1: Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3121-7.

Topical combination of NGF and DHA increases rabbit corneal nerve regeneration
after photorefractive keratectomy.

Esquenazi S, Bazan HE, Bui V, He J, Kim DB, Bazan NG.

LSU Eye Center, LSU Health Sciences Center, School of Medicine, Louisiana State
University, 2020 Gravier Street, New Orleans, LA 70112, USA.

PURPOSE: To investigate the effect of nerve growth factor (NGF) in combination
with docosahexaenoic acid (DHA) on corneal nerve regeneration in a rabbit model
after PRK and correlate the findings with functional tear test. METHODS:
Unilateral PRK was performed on 21 New Zealand albino rabbits. Three groups, each
consisting of six rabbits, were randomized to receive twice-weekly treatments
with DHA, NGF, or NGF plus DHA delivered by collagen shield. A fourth group, the
control, received treatment with albumin. Rabbits were observed for 8 weeks, and
tear secretion tests were conducted every 15 days. The eyes were prepared for
immunostaining. Monoclonal antibodies for class II beta-tubulin, calcitonin
gene-related peptide (CGRP), substance P (SP), and Ki-67 were used. Cell nuclei
were stained with 4',6'-diamino-2-phenylindole (DAPI). Positive staining areas in
relation to total area were calculated with image-analysis software. RESULTS:
There were no significant differences in the tear-secretion test results among
the four groups. However, none of the eyes treated with NGF plus DHA showed rose
bengal staining 30 days after PRK, compared with 50% in the control group and 33%
in the DHA-treated group. A higher percentage of Ki-67-positive cells, a marker
of cell proliferation, was observed in the DHA plus NGF-and NGF-treated groups
compared with DHA alone or the control. Eight weeks after PRK, tubulin-positive
and CGRP-positive epithelial and subbasal nerve bundle areas were significantly
higher in the DHA plus NGF group than in the control and NGF or DHA alone. No
differences were noted in the SP-positive nerve bundles between the different
treatments and the control treatment. CONCLUSIONS: NGF plus DHA treatment after
PRK in rabbits is associated with increased corneal nerve surface area, increased
epithelial proliferation, and decreased rose bengal staining compared with NGF,
DHA, or vehicle control alone. The combination of NGF plus DHA yields faster
nerve recovery after PRK and may have therapeutic usefulness in the treatment of
post-PRK dry eye and other neurotrophic keratopathies.


PMID: 16123410 [PubMed - indexed for MEDLINE]

[Jenny1976]

Hallo Denise18,
ich habe die auch mal eine Zeit genommen und hatte das Gefühl das sie mir geholfen haben. Ich glaub ich hatte sie nen 1/4 Jahr genommen und hatte dann für gut ein Jahr ruhe oder das Gefühl keine Beschwerden mehr zu haben.

Seitdem ich keine Kontaktlinsen mehr trage, habe ich aber zum Glück eh keine größeren Probleme mit trockenen Augen. Bin gespannt wie das nach der Femto wird.

Liebe Grüße Jenny